It's like a story right out of "CSI."

News 13 has uncovered new information in a murder mystery in Orlando, where a man first thought to have taken his own life is now being called a murder victim.

It wasn't until the medical examiner took a closer look at the stab wound in Confesor "J.R." Rodriguez's neck that detectives reclassified his death from suicide to homicide.

The victim's sister, Shirley VanGlahn, spoke Tuesday during a news conference at the Orlando Police Department.

"I miss my brother, and my brother was taken away from us," said VanGlahn, with tears in her eyes.

"J.R." was 43 years old and lived on East Esther Street, just across from Boone High School, in a home he owned since 2006, according to records from the Orange County property appraiser.

The Orange County circuit clerk's website showed Rodriguez may have been in the process of a foreclosure with pending cases involving a bank.

Detectives said he lived alone and kept to himself, which is why his family said they can't make sense of his death.

"My brother was full of life, full of love, loved his family and was very successful in everything he did in life," VanGlahn said.

When police arrived at the home on Nov. 18, they initially ruled his death a suicide. Detectives said it was because nothing inside the home was ransacked or stolen.

That's what makes Rodriguez's death even more of a mystery, according to Orlando homicide Detective Chris Haas.

"This is a man who got murdered in his own home," said Haas. "Confesor Rodriguez had no negative contacts with the police, never been arrested. He worked hard, worked out, minded his own business, and he was brutally murdered in his own home."

It was only after an autopsy report that investigators learned it was not a self-inflicted death. According to the medical examiner, Rodriguez died from stab wounds to the neck.

But with little evidence and no signs of who did this, Rodriguez's family is left looking for answers.